WebGeneric Name Lenalidomide DrugBank Accession Number DB00480 Background. Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. 4 It is a 4-amino-glutamyl analogue of thalidomide 3 and like thalidomide, lenalidomide exists as a racemic mixture … WebWhen Myocet liposomal 2is administered in combination with cyclophosphamide (600 mg/m ) the initial recommended dose of Myocet liposomal is 60-75 mg/m2 every three weeks. Older people . Safety and efficacy of Myocet liposomal have been assessed in 61 patients with metastatic breast cancer, age 65 and over.
Cyclophosphamide Side Effects, Warnings, Dosage, and More
WebCyclophosphamide is in a class of medications called alkylating agents. When cyclophosphamide is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When cyclophosphamide is used to treat nephrotic syndrome, it works by suppressing your body's immune system. How should this medicine be used? WebWhereas drugs like colchicine cause the depolymerization of microtubules in vivo, docetaxel arrests their function by having the opposite effect; it hyper-stabilizes their structure. This destroys the cell's ability to use its cytoskeleton in a flexible manner. ... Cyclophosphamide: The metabolism of Docetaxel can be increased when combined ... countdown semafori
Rivaroxaban: Uses, Interactions, Mechanism of Action - DrugBank
WebIfosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent. Type Small Molecule ... At doses of 1.6–2.4 g/m2 only 12% to 18% of the dose was excreted in the urine as unchanged drug within 72 hours. Half-life ... WebSeven percent to 20% of the parent drug is excreted unchanged in the urine in 6 hours; of this over 90% is excreted in the first hour. The remaining percentage of the administered dose is metabolized, primarily in the … WebDacarbazine is an antineoplastic agent used to treat malignant melanoma and Hodgkin's disease. Generic Name Dacarbazine DrugBank Accession Number DB00851 Background An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). brenda lee early video