WebJan 16, 2024 · In the experimental group, with a concentration of 0.1 g/ml of cisplatin, about 37% of the cells were alive and about 6% of the cells had primary apoptosis. More than 42% of the cells had secondary apoptosis and about 14% of the cells had necrosis. WebNov 7, 2024 · Cisplatin efficiently induced cell death in OVCAR-3, OVCAR-4, and IRGOV-1 (>60% cell death) whereas OVCAR-5, OVCAR-8, and A2780 showed <30% apoptotic cells in response to cisplatin. Based on...
Cytotoxic effects and apoptosis induction of cisplatin-loaded …
WebJan 16, 2024 · In the experimental group, with a concentration of 0.1 g/ml of cisplatin, about 37% of the cells were alive and about 6% of the cells had primary apoptosis. … WebApr 25, 2014 · The dosage of cisplatin determines whether the cells die by necrosis or apoptosis [30]. In cell culture studies, high concentrations of cisplatin cause necrotic cell death but lower concentrations lead to apoptosis. However,in vivo, cisplatin induces both necrosis and apoptosis [31]. career services regent school of divinity
Effect of naringenin and its combination with cisplatin in cell …
WebSep 30, 2024 · Both cisplatin and onalespib were diluted further in complete media for assay dependent concentrations. The final DMSO concentration was 0.005% (v/v) for 3000 nM Onalespib, 0.0002% (v/v) and 0.00008% (v/v) for 100 nM for 50 nM, respectively. XTT Cell Viability Assays WebAbstract Cisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. ... adenocarcinoma promotes proliferation via the accumulation of β-catenin 17 and regulates lung tumorigenesis through cell apoptosis and autophagy pathways. 16 USP14 is critical ... WebJan 1, 2007 · Cisplatin is a broad-spectrum anticancer drug that is also widely used in experimental studies on DNA damage-induced apoptosis. Induction of apoptosis … brooklyn meadows apartments mooresville in